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The grmsem package is a quantitative genetics tool supporting the modelling of multivariate genetic variance structures in quantitative data. grmsem allows fitting different models through multivariate genetic-relationship-matrix (GRM) structural equation modelling (SEM) in unrelated individuals, using a maximum likelihood approach. Specifically, it combines genome-wide genotyping information, as captured by GRMs, with twin-research-based SEM techniques. |
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